Reaching delta sleep is restorative to the body and mind.
Some antidepressants interfere with reaching delta states.
In general, antidepressants tend to suppress REM sleep and increase the time taken to enter REM sleep. ... In some studies, selective serotonin reuptake inhibitors (SSRIs), like sertraline and fluoxetine, have been shown to disturb/fragment sleep.


Its up to you to tinker or rely on nature